The Asthma and Allergy Foundation of America’s annual ranking of the worst cities for people with spring allergies is out, and once again, the Southeastern United States appears to fare worst, thanks to a combination of warm weather and pollen counts.

But as there are more than 45 million Americans who have pollen and/or grass allergies, no region is really safe from the season, Dr. Clifford W. Bassett, medical director of Allergy and Asthma Care of New York and an ambassador for the AAFA, told One in five people has the “allergic gene,” which means that even if you move away from a pollen-heavy area, you’ll develop new allergies in your new hometown after a couple of years, he added.

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